STAT3 and neoplasm: To investigate the correlation between STK24 expression and STAT3/VEGFA signaling pathway during tumor angiogenesis, the present study constructed NSCLC cell lines stably expressing vector+shnc, STK24+shnc, STK24+shSTAT3#1, or STK24+shSTAT3#2 and used immunoblot analysis to confirm the stable expression (Fig. 6A).