Similar observations were made in noise exposure animal studies, where RAAS activation was prominent as documented by elevated angiotensin-II levels (Munzel et al, 2017a), additive damage of noise in mice with arterial hypertension by angiotensin-II infusion (Steven et al, 2020), and normalization of elevated blood pressure in noise-exposed mice by the ACE inhibitor captopril (Frenis et al, 2021b). The gene discussed is ACE; the disease is Hypertension.