Likewise, eNOS S-glutathionylation, enhanced endothelial ROS formation, and endothelial dysfunction are the result of exposure of mice to aircraft noise around-the-clock (Fig. 3) (Munzel et al, 2017a), in particular, of exposure during the sleep phase (Kroller-Schon et al, 2018). This evidence concerns the gene NOS3 and endothelial dysfunction.