Furthermore, analysis of human control and MS tissues confirmed juxtapositioning of OL-KIR4.1 and NoR-Kv7.2 channels in normal-appearing WM (NAWM) and periplaque WM (PPWM) lesion rim areas of ON tissues from patients with MS based on myelin oligodendrocyte glycoprotein (MOG) immunoreactivity (IR) (Figure 1B and Supplemental Table 1; supplemental material available online with this article; https://doi.org/10.1172/JCI164223DS1). The gene discussed is KCNQ2; the disease is myeloid sarcoma.