AKT2 and hepatocellular carcinoma: In addition, AKT2 (AKT Serine/Threonine Kinase 2) upregulation plays a critical role in carcinogenesis, metastasis, and angiogenesis, which can be employed as an anti-cancer target in hepatocellular carcinoma (Wang et al. 2016), ovarian cancer (Lin et al. 2018), and CC (Chen et al. 2020).