In the case of non life-treathening manifestations and the presence of generalized active disease patients will usually require therapy with cytotoxic agents including, azathioprine, methotrexate, mycophenolate mofetil or cyclophosphamide [14] with the evidence of a beneficial effect of anti-interleukin-5 monoclonal antibodies in EGPA [15]. Here, IL5 is linked to eosinophilic granulomatosis with polyangiitis.