The distribution of the percentage of change in tumor diameter and corresponding MIB2 protein levels in tumor specimens is summarized in Figure 8F. Notably, we found that the protein levels of MIB2 but not those of PD-L1 were positively correlated with changes in tumor size after 3 months of PD-1 mAb treatment (Figure 8, G and H). Here, MIB2 is linked to neoplasm.