However, apart from potentiating inflammation, ATM exerts crucial beneficial effects during obesity including induction of lysosomal genes in ATM [172], stimulation of lysosomal exocytosis along with enhanced expression of lipid metabolism genes to handle the excess fat in obese AT, while inflammatory mediators facilitate recruitment of additional macrophages to CLS enabling efficient clearance of dying adipocytes [173]. The gene discussed is ATM; the disease is Obesity.