Consistently, under hypoxia, lv-FTO transduction suppressed glioma cell viability (Figure 6B), cell migration (Figure 6C), and cell invasion (Figure 6D), whereas agomir-27a-3p exerted opposite effects on glioma cell phenotypes (Figure 6B–D); similarly, the oncogenic effects of agomir-27a-3p on glioma cells were partially diminished by lv-FTO (Figure 6B–D). Here, FTO is linked to central nervous system cancer.