FTO and central nervous system cancer: We divided cases from the Chinese Glioma Genome Atlas (CGGA)-mRNAseq (n=325) into high- and low-FTO expression groups based on the median FTO expression; the association between the expression level of FTO and the survival of glioma patients was analyzed using the R language package Survminer and Survival [25,26] .Figure 2D shows that higher FTO expression was correlated with better prognosis in glioma patients.