Since previous studies reported that Becn1 was an important autophagy-related gene, but a recent finding (Kang et al., 2018) revealed that Becn1 was meanwhile a new driver of ferroptosis, which promoted ferroptosis through formatting Becn1-SLC7A11 complex to inhibit the cysteine and glutamate antiporter system Xc- activity in cancer cells. Here, BECN1 is linked to cancer.