SCENIC analysis also indicated that Atf3 regulon activity in the Sephin1 group in tumor tissue was higher in antitumor cell types such as NK cells, NKT cells, and Cd8+ T cells but lower in the suppressive T cell type, regulatory Cd4+ T cells,64 which also indicated the antitumor suppression effects of Sephin1. Here, CD8A is linked to neoplasm.