For example, in a study of 3886 healthy controls and 72 COVID-19 patients by Lorente et al. the HLAA*32 allele was found to be a protective allele, whereas the frequency of the HLA-C*16 and HLA-B*39 alleles was higher in infected individuals; however, the results were not statistically significant [53]. This evidence concerns the gene HLA-B and COVID-19.