Because the homology and pathogenicity mechanism of SARS-Co-V are very similar to COVID-19, the HLAs likely mentioned in various studies, such as HLA-A*02:01, HLA-A*02:06, HLA-A*24:02, HLA-B*15:03, HLA-B*44, C*01, HLA-A*25, and HLA-B*08, also play a vital role in susceptibility or resistance to COVID-19 [39, 43, 44]. This evidence concerns the gene HLA-S and COVID-19.