LGMN and Alzheimer disease: Moreover, after FMT treatment, the protein levels of C/EBPβ and AEP were significantly decreased in the brains of the PA-FMT-treated TgCRND8 mice, as compared with the vehicle-treated TgCRND8 control mice, which further demonstrated that PA could exert anti-AD effects by modulating gut microbiota via inhibition of the activation of C/EBPβ/AEP signaling pathway in TgCRND8 mice.