Efficacy studies showed that both RSC and WSC induced an increase in IFN-γ levels and a decrease in IL-4 and IgE levels and improved lung inflammation (Fig. 2B, C), suggesting that these substances could play a role in the treatment of asthma by regulating the imbalance of the Th1/Th2 ratio and reducing IgE levels. This evidence concerns the gene IGHE and asthma.