CRP and HIV infectious disease: In this community-based, cross-sectional study in a mixed urban and rural population from the North West province of South Africa, we observed that risk factors associated with eGFR < 90 ml/min/1.73m2 and/or uACR ≥ 3.0 mg/mmol included HIV infection, elevated SBP, and elevated CRP (a non-specific marker of systemic inflammation).