When we investigated the top 10 most informative genes based on the SNV information, we found “PTEN” are “APC” genes, which are known tumor suppressors; “MUC16” gene, which is a biomarker for ovarian cancer; “ZFHX3” gene, which is implicated in prostate cancer; “CCDC168” gene, which is known to be associated with Prostate Carcinoma and Uterine Body Mixed Cancer. The gene discussed is ZFHX3; the disease is Familial prostate cancer.