The level of FTO was significantly decreased in the somatosensory cortex of AIS patients compared with nonstroke controls (Fig. 2c), whereas there were no significant differences in the levels of METTL3, METTL14, WTAP, and ALKBH5 (Supplementary Fig. 4a, b). The gene discussed is ALKBH5; the disease is androgen insensitivity syndrome.