Secretion of proinflammatory cytokines (interferon-gamma and tumor necrosis factor-alpha) is critical in the inflammatory cascade induced through the activation of macrophages, cytotoxic T lymphocytes, natural killer cells, and neutrophils and is reduced in stem cells.24In rats with HL that had receiving DPSCs and SHED transplants, we observed that the number of SGNs increased significantly at the basal turn region of the cochlea after 4 to 10 weeks of transplantation. This evidence concerns the gene TNF and Hodgkins lymphoma.