In addition, cancer cells are particularly sensitive to Hsp90 inhibitors (Miyata et al. 2013), possibly attributed to post-translational modifications (Backe et al. 2020), conformational changes of Hsp90 (Beebe et al. 2013) and/or an increased degree of connectivity within the chaperome network, termed the epichaperome. Here, HSP90AA1 is linked to cancer.