IFNG and infection: The precise mechanisms of disruption appear to differ in different infections, but likely involve host-derived cytokines and chemokines, with type 1 interferons, lymphotoxin, and interferon gamma being implicated in studies using LCMV, Toxoplasma gondii, and Plasmodium respectively (Keitany et al., 2016; Daugan et al., 2016; Glatman Zaretsky et al., 2012).