Furthermore, progeroid laminopathies (including classic and non-classic Hutchinson-Gilford progeria syndrome) were reported not to exhibit epigenetic age acceleration as observed in Werner syndrome or CGL2, which suggests that accelerated aging in progeroid laminopathies is not related to the biological aging processes measured via epigenetic clocks (33). The gene discussed is GZMH; the disease is Hutchinson-Gilford progeria syndrome.