The AA genotype was significantly higher in patients with pre-B-cell ALL than that in the non-ALL children (OR = 1.41, 95% CI = 1.042–1.908, P = 0.026; Table 1), indicating the susceptibility of GATA3 rs3824662 in pre-B-cell leukemia. This evidence concerns the gene GATA3 and acute lymphoblastic leukemia.