The consensus guideline from the 2016 Cincinnati International Turner Syndrome meeting suggested that concomitant treatment with oxandrolone from ≥10 years of age at 0.03 mg/kg/day and maintained at <0.05 mg/kg/day, if the diagnosis of TS and GH treatment initiation is delayed, and/or AH outcome is likely to be unsatisfactory with the standard GH dose alone (41). This evidence concerns the gene GH1 and Turner syndrome.