Regarding the role of each involved OAG, it was noticed that the lower expression of ATHL1 but higher expression of GABRR1, KCNH2, RIBC2, PDE6A, and PDX1 was significantly correlated with the response of sorafenib treatment in HCC (p < 0.05, Figure 8B). Here, PDE6A is linked to hepatocellular carcinoma.