Furthermore, results of KEGG pathway analysis showed that the candidate genes were primarily enriched in RNA transport, type 1 DM, TFG-β signaling pathway, bladder cancer, endometrial cancer, longevity regulating pathway, TNF signaling pathway and inflammatory bowel disease, progesterone-mediated oocyte maturation, NF-kappa B signaling pathway, cholesterol metabolism and inostiol phosphate metabolism (Figure 4C). Here, TNF is linked to inflammatory bowel disease.