However, in contrast, plaque coverage did not drop off in the SR-B1 KO mice in the thoracic aorta (∼40%, Figure 3G) and decreased (<20%) only in the abdominal regions (Figure 3H) of aortas, extending to the iliac bifurcation, which was generally atherosclerosis free in the LDLR and ApoE KO mice. This evidence concerns the gene LDLR and atherosclerosis.