APOE and atherosclerosis: However, in contrast, plaque coverage did not drop off in the SR-B1 KO mice in the thoracic aorta (∼40%, Figure 3G) and decreased (<20%) only in the abdominal regions (Figure 3H) of aortas, extending to the iliac bifurcation, which was generally atherosclerosis free in the LDLR and ApoE KO mice.