CD16+CD38+CD4+ naive T cells (defined as CD45RA+CD45RP–CCR7+CD27+) were detected to synergistically overexpress CXCR3 and CCR6 cytokines, and they were enriched in CDa with statistical significance comparing with CDin (P < 0.05, Figure 1C). The gene discussed is CXCR3; the disease is congenital dyserythropoietic anemia.