COVID-19 patients with hyponatremia also had higher SARS-CoV-2 viral loads (Ct values 22.2 ± 6.4 vs. 23.5 ± 6.8, P < 0.001), C-reactive protein (CRP) (6.7 ± 7.1 vs. 3.7 ± 5.9 mg/L, P < 0.001), creatine kinase (410 ± 1491 vs. 250 ± 1599 U/L, P < 0.001), and D-dimer levels (1284 ± 1871 vs. 862 ± 1567 ng/mL, P < 0.001) than those without hyponatremia (Tables 1, 2). Here, CRP is linked to Hyponatremia.