Our acetylomics data showed significant differences in acetylation modification in ACADS and ACADSB, but not in acetyl-CoA oxidase (ACOX); similarly, no study has yet assessed the correlation between ACOX and COPD, indicating that the differential acetylation of ACADS rather than ACOX may be involved in COPD. This evidence concerns the gene ACADSB and chronic obstructive pulmonary disease.