Furthermore, topical application of myristoylated CCR10 binding domain 7 amino acid (Myr-CBD7) peptide prevented CCR10-eNOS interaction and subsequent eNOS downregulation, enhanced eNOS/NO levels, and improved wound healing in obesity-induced diabetic mice (Chen et al., 2022). The gene discussed is NOS3; the disease is obesity due to melanocortin 4 receptor deficiency.