Age [hazard ratio (HR) = 1.033, P < 0.001], estrogen receptor (HR = 0.670, P = 0.048), progesterone receptor (HR = 0.672, P = 0.037), pathologic stage (stage III vs. stage I, HR = 3.115, P < 0.001; stage IV vs. stage I, HR = 10.534, P < 0.001), T stage (T4 vs. T1, HR = 4.608, P < 0.001), M stage (M1 vs. M0, HR = 6.657, P < 0.001), N stage (N1 vs. N0, HR = 1.538, P = 0.048; N2 vs. N0, HR = 2.725, P < 0.001; N3 vs. N0, HR = 5.290, P < 0.001), and risk score (HR = 1.418, P < 0.001) were correlated with OS of breast cancer patients (Figure 3A). The gene discussed is PGR; the disease is breast cancer.