Multivariate analysis revealed that apoB (HR=0.04, 95% CI, 0.00-1.00; P=0.050), CHO (HR=0.34; 95% CI, 0.12-0.94; P=0.038), Age (HR=1.02; 95% CI, 1.00-1.04; P=0.032), CRC with hepatic metastasis (HR=1.57; 95% CI, 1.02-2.41; P=0.040), LDL-C (HR=2.79; 95% CI, 1.07-7.28; P=0.036), HDL-C (HR=4.18; 95% CI, 1.16-15.12; P=0.029), apoA1 (HR=5.96; 95% CI, 1.47-24.17; P=0.012) and apoB/A ratio (HR=107.07; 95% CI, 5.75-1993.74; P=0.002) were independently prognostic factors for OS (Figure 3). The gene discussed is APOB; the disease is colorectal carcinoma.