In addition, elevated IL27 expression could induce an enhanced immune response and pyroptosis (R = 0.64, p = 1.2e−55), autophagy (R = 0.37, p = 7.1e−17), and apoptosis (R = 0.47, p = 1.1e−27) in patients with melanoma (30–34). Here, IL27 is linked to melanoma.