IFNB1 and colorectal cancer: qRT-PCR analyses of infected HT29 cell lines, a human colorectal cancer cell line possessing deficient, but still active signaling, demonstrated that STINGPOX activated IFNB1 (a type I IFN) and RSAD1 (a downstream interferon stimulated gene; ISG) expression to significantly higher levels than the parental OncoVACV (Figures 3F, G).