In patients with a more severe upper respiratory tract infection, the SARS CoV-2 infection often causes a mild and/or severe acute respiratory syndrome (SARS) with subsequent release of cytokines/mediators such as: interleukin (IL)-1β, IL-2, IL-4, IL-5, IL-6, IL-7, IL-8 (CXCL8), IL-10, IP10, IL-12, IL-13, IL-17, IL-33, IL-25, IL-37, IL-38, GCSF, GM-CSF, HGF, IP-10, MCP-1, MIP-1α, IFN-γ, IFN-α, TRAIL, MCSF, and TNF-α (1). This evidence concerns the gene CXCL8 and Recurrent upper respiratory tract infections.