The allelic frequencies of cancer patients were not significantly different from that of controls (P = 0.925); The C/C genotype had no increased risk for cervical cancer susceptibility compared with the TT genotype (P = 0.932). There was no significant relationship between the ERCC1 C19007T polymorphism and cervical cancer invasiveness (all P<0.05). Here, ERCC1 is linked to cancer.