TET2 and myelodysplastic syndrome: Morphologic assessment showed increased marrow cellularity and dysmorphic cells, especially very large and small erythroblasts, hypolobulated neutrophil and asymmetric binucleation (Figures 1D, E); FCM showed 1.49% blasts and 39.9% lymphoid cells in BM; the karyotype analysis showed 46, XY (Figure 1F); MDS-associated genes panel revealed the TET2 mutation (c.3986T>C, VAF of 35.4%; c.4100C>G, VAF of 37.3%; c.4250T>G, VAF of 2%).