As the clustering heatmap shown in Figure 6, EgPSC infection significantly downregulated the expression of innate immunity moleculars (Pecam1, Tlr5, Ccl12, Cxcr3, Ccl9, Ccl5, Ccl3, Cxcl12, Cxcr6, Ccr10, and Ccr5), adaptive immunity components (Pecam1, Cxcr3, Ifi47, Flt3l, Tigit, Cd3e, Lepr, Cd8b1, Csf1r, Fasl, Cd4, and Cd28), immunomodulatory factors (Cd72, Stat4, and Csf1r), immune response moleculars (Flt3l, Mapk9, and Cd3e), cytokines (Il15, Il12rb1, Il2rb, and Il21r). Here, IL21R is linked to infection.