A number of adhesion molecules have been identified as being involved early in the disease course of AP, including intercellular adhesion molecule-1 (ICAM-1 or CD54), vascular cell adhesion molecule-1 (VCAM-1), E-selectin, Integrin alpha L (CD11a) and Integrin alpha M (CD11b). The gene discussed is ITGAM; the disease is alkaline phosphatase measurement.