Notably, studies show that the NF-κB signal pathway is a central pathway involved in induction of pro-inflammatory cytokines and chemokines in respiratory virus infection, including SARS-CoV-2-triggered COVID-19 (Kircheis et al., 2020; Hariharan et al., 2021; Kandasamy, 2021). Here, NFKB1 is linked to COVID-19.