TOLLIP and infection: Interestingly, the correlation analysis between intestinal microbial variation and host immunity showed that an elevated abundance of Photobacterium and Vibrio could increase expression of Tollip and NF-κB inhibitor cactus-like, suggesting that the expansion of Photobacterium and Vibrio in DIV1 infection could be a key factor to limit TLR-mediated immune response, which may ultimately lead to further infection of DIV1.