CALCA and Cirrhosis: (3) The intake of calcium in patients with chronic liver disease and cirrhosis is reduced due to poor intake, vomiting and diarrhea; (4) In cirrhosis, the cell membrane of liver cannot carry out normal ion operation, and a large amount of blood calcium flows into the cytoplasm, which further decreases blood calcium, and also affects the synthesis and secretion of parathyroid hormone and calcitonin.