Based on the TCGA database, the expression of ANXA2 in cervical squamous cell carcinoma (CESC), CHOL, COAD, esophageal carcinoma (ESCA), GBM, head and neck squamous cell carcinoma (HNSC), kidney renal clear cell carcinoma (KIRC), kidney renal papillary cell carcinoma (KIRP), LIHC, STAD, thyroid carcinoma (THCA) and uterine corpus endometrial carcinoma (UCEC) was higher compared with corresponding normal tissues. This evidence concerns the gene ANXA2 and head and neck squamous cell carcinoma.