The expression of ANXA2 positively correlated with DNA methylation in BLCA (r = .162, p = .001), BRCA (r = .075, p = .035), CESC (r = .135, p = .019), ESCA (r = .257, p = .001), HNSC (r = .146, p = .001), LUSC (r = .114, p = .029), SKCM (r = .102, p = .027), TGCT (r = .567, p < .001), UCEC (r = .210, p < .001) and UCS (r = .363, p = .006) and negatively correlated with DNA methylation in sarcoma (SARC) (r = −.198, p = .001), STAD (r = −.244, p < .001) and THYM (r = −.355, p < .001) (Figure 8A). The gene discussed is ANXA2; the disease is sarcoma.