Interestingly, overexpression of carnitine/acylcarnitine transporter (CACT), a mitochondrial membrane protein responsible for the transport of acylcarnitine into mitochondrial matrix for oxidation, in a HCC cell line and human HCC tumor tissue has been shown to suppress cancer growth and migration due to increased FAO (Yuan et al., 2021). The gene discussed is SLC25A20; the disease is hepatocellular carcinoma.