Specifically, great interest has been given to IL-1β which is increased in several cancers and has proven to promote tumorigenesis, tumor invasiveness (Zhou et al., 2022) and immunosuppression (Krelin et al., 2007; Carmi et al., 2013; Voronov and Apte, 2020; Zhou et al., 2022). This evidence concerns the gene IL1B and neoplasm.