Moreover, these two domains are often lost in leukemic protein fusions with MOZ/MORF produced by chromosomal translocations (Borrow et al., 1996; Carapeti et al., 1998; Chaffanet et al., 2000), which indicates that lack of these domains may deregulate the MOZ-dependent gene expression network, leading to cancer. Here, KAT6A is linked to cancer.