BRPF1 and Bone marrow hypocellularity: Similar to MOZ mutations, patients with BRPF1 mutations do not show hematological abnormalities (Mattioli et al., 2017; Yan et al., 2017; Demeulenaere et al., 2019; Pode-Shakked et al., 2019; Naseer et al., 2020; Yan et al., 2020), although loss of BRPF1 leads to acute bone-marrow failure in mice (You et al., 2016).