In our study, the relationship between CEACAM1 expression level and clinicopathological characteristics of ccRCC patients was evaluated, and the results of chi-square test or Fisher's exact test have shown that CEACAM1 expression was negatively correlated with tumor size status (P < 0.001), metastasis status (P = 0.009), pathological stage (P = 0.002), and histological grade (P < 0.001) but positively correlated with primary treatment outcome (P = 0.045), and CEACAM1 expression was higher in male patients than in female patients. This evidence concerns the gene CEACAM1 and nonpapillary renal cell carcinoma.