IRF4 and central nervous system cancer: We performed qRT-PCR analysis and found that the expressions of TNFAIP6 (Figure 2C), PSMB2 (Figure 2D), IRF4 (Figure 2E) and IFNAR2 (Figure 2F) were significantly upregulated in glioma tissues (n = 30) compared to normal brain tissues (n = 10).