Not only that, more and more experiments have shown that P53 is related to the death of neurons in animal experimental models of cerebral ischemia or hypoxia (Banasiak and Haddad, 1998; Leker et al., 2004; Endo et al., 2006; Yonekura et al., 2006; Damisah et al., 2020). This evidence concerns the gene TP53 and brain ischemia.