Not only that, more and more experiments have shown that P53 is related to the death of neurons in animal experimental models of cerebral ischemia or hypoxia (Banasiak and Haddad, 1998; Leker et al., 2004; Endo et al., 2006; Yonekura et al., 2006; Damisah et al., 2020). Here, TP53 is linked to Cerebral ischemia.