ZFPM2-AS1 and MIR210HG have previously been reported to be involved in cell proliferation and migration (Li J. et al., 2017; Kang et al., 2019; Wang Y. et al., 2019; He et al., 2020; Liu et al., 2020; Wang et al., 2020), indicating that the model composed of these two lncRNAs is not only an indicator of genomic instability, but also can predict the prognosis in patients with HCC. The gene discussed is ZFPM2; the disease is hepatocellular carcinoma.