LGALS1 and nonpapillary renal cell carcinoma: In addition, some of their findings were completely consistent with our study, including LGALS1 mRNA expression in ccRCC is significantly higher than normal kidney tissue of the same patient, patients with high LGALS1 expression are correlated with poor overall survival and disease-free survival, and compared with low-grade (grade I or II) tumors, high expression levels of LGALS1 are correlated with high-grade tumors (grade III or IV) (White et al., 2014).